Details
Technique | Tomo-seq |
---|---|
Title | Spatially resolved RNA-sequencing of the embryonic heart identifies a role for Wnt/β-catenin signaling in autonomic control of heart rate |
PMID | 29400650 |
Description | Development of specialized cells and structures in the heart is regulated by spatially -restricted molecular pathways. To better understand these pathways and how they regulate cardiac development this study used tomo-seq, combining high-throughput RNA-sequencing with tissue-sectioning, to establish a genome-wide expression dataset with high spatial resolution for the developing zebrafish heart. |
Source | TL wildtype hearts dissected from live 2-day-old zebrafish embryos |
Species | zebrafish |
No. genes | 16023 genes |
No. cells | NA |
Resolution | cellular |
Data normalization | Spike-in normalization |
Data availability | GSE104057 |